Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773573 | 0.87 | PRKCA (0.50) | PRKCAMMP12NR1I2 | |
| SCHEMBL804595 | 0.81 | NR1I2 (0.36) | PRKCAMMP12NR1I2DRD2DRD1 | |
| SCHEMBL771845 | 0.76 | PRKCA (0.51) | PRKCAMMP12NR1I2 | |
| SCHEMBL771869 | 0.75 | PRKCA (0.56) | PRKCAMMP12NR1I2 | |
| SCHEMBL772016 | 0.74 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL10283222 | 0.73 | PRKCA (0.48) | PRKCAMMP12NR1I2 | |
| Hydrochloric Acid SCHEMBL772936 | 0.73 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL773796 | 0.72 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL804583 | 0.72 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL803702 | 0.72 | PRKCA (0.36) | PRKCAMMP12NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | PRKCA 2404/4885MMP12 1013/4885NR1I2 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.