Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.63 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12665013 | 0.79 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL10284628 | 0.79 | TAS2R8 (0.61) | TAS2R8 | |
| SCHEMBL12362595 | 0.77 | TAS2R8 (0.75) | TAS2R8TAS2R14 | |
| SCHEMBL1279236 | 0.77 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL12665004 | 0.77 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL12062565 | 0.76 | TAS2R8 (0.62) | TAS2R8 | |
| SCHEMBL12665937 | 0.74 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL18351075 | 0.69 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL12666739 | 0.69 | TAS2R8 (0.61) | TAS2R8 | |
| SCHEMBL1279356 | 0.66 | TAS2R8 (1.00) | TAS2R8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148544-B2 | Compounds that inhibit (block) bitter taste in composition and methods of making same | SENOMYX, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20110207937-A1 | Compounds that inhibit (block) bitter taste in composition and methods of making same | SENOMYX, INC. (US) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207937-A1 | Compounds that inhibit (block) bitter taste in composition and methods of making same | TAS2R50, TAS2R1, TAS2R5 | TAS2R8 19/4885TAS2R14 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.