⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533257 | 0.83 | — | — | |
| SCHEMBL6572498 | 0.79 | — | — | |
| SCHEMBL12715403 | 0.77 | — | — | |
| SCHEMBL4552340 | 0.77 | — | — | |
| SCHEMBL15901770 | 0.74 | MAOA (0.38) | — | |
| SCHEMBL21872484 | 0.74 | MAOA (0.40) | — | |
| SCHEMBL12061582 | 0.74 | MAOA (0.38) | — | |
| SCHEMBL6684603 | 0.74 | MAOA (0.38) | — | |
| SCHEMBL5958814 | 0.73 | — | — | |
| SCHEMBL2973151 | 0.72 | MAOA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274302-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2011-01-19 | — | — | EP | claimed |
| WO-2009123948-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-10-08 | — | — | WO | claimed |
| CN-120118077-A | Compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119730855-A | Application of steroid compound in preparation of medicine for preventing and/or treating ophthalmic diseases | 广州润尔眼科生物科技有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119708106-A | Steroid compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119708105-A | Steroid compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119661620-A | Steroid compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119661618-A | Steroid compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119255807-A | Application of steroid compound in preparation of medicine for preventing and/or treating presbyopia | 广州润尔眼科生物科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119212711-A | Use of steroid compounds | 广州润尔眼科生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-119101108-A | Steroid compound and application thereof | 广州润尔眼科生物科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20150231127-A1 | BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF | BARRY UNIVERSITY, INC. | 2015-08-20 | — | — | US | disclosed |
| US-20150231127-A1 | BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF | BARRY UNIVERSITY, INC. | 2015-08-20 | — | — | US | disclosed |
| EP-2785695-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-10-08 | — | — | EP | disclosed |
| US-20140018366-A1 | BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF | BARRY UNIVERSITY, INC. | 2014-01-16 | — | — | US | disclosed |
| US-20140018366-A1 | BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF | BARRY UNIVERSITY, INC. | 2014-01-16 | — | — | US | disclosed |
| US-20130143863-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2013079452-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-06 | — | — | WO | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-20060211678-A1 | Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds | OSI PHARMACEUTICALS, INC. | 2006-09-21 | — | — | US | disclosed |