Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26880353 | 0.88 | ALDH1A1 (0.48) | LMNAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL22826051 | 0.82 | DPP4 (0.44) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15726987 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL15080935 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL1687958 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL478542 | 0.79 | — | — | |
| SCHEMBL12142184 | 0.79 | — | — | |
| SCHEMBL4760538 | 0.79 | — | — | |
| SCHEMBL23997789 | 0.78 | ALDH1A1 (0.47) | LMNAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL19629191 | 0.77 | ALDH1A1 (0.39) | LMNAALDH1A1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |