Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286331 | 1.00 | P2RX7 (0.44) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL2171553 | 1.00 | P2RX7 (0.44) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL30979862 | 1.00 | P2RX7 (0.44) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9741792 | 0.98 | P2RX7 (0.44) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL10286357 | 0.95 | P2RX7 (0.45) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL1514902 | 0.95 | P2RX7 (0.45) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL29472109 | 0.95 | P2RX7 (0.45) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL5021376 | 0.95 | P2RX7 (0.45) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL3314142 | 0.87 | OPRL1 (0.49) | P2RX7OPRL1KCNH2HDAC1HDAC6 | |
| SCHEMBL17549915 | 0.87 | OPRL1 (0.49) | P2RX7OPRL1KCNH2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121472345-A | Method for preparing (9S) -6,7,8, 9-tetrahydro-9-hydroxy-5H-cyclohepta [ b ] pyridin-5-one by catalyzing alcohol dehydrogenase | 浙江九洲药业股份有限公司 | 2026-02-06 | — | — | CN | disclosed |
| CN-115060824-B | Liquid chromatography detection method for enantiomer impurities of ramiazepam intermediate | 浙江宏元药业股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115060824-B | Liquid chromatography detection method for enantiomer impurities of ramiazepam intermediate | 浙江宏元药业股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20130102631-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102631-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2012001040-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102631-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | MSR1, DDT, MPO | P2RX7 445/4885OPRL1 3991/4885KCNH2 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.