Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458677 | 0.77 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL458213 | 0.72 | KDM4E (0.38) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL469922 | 0.71 | KDM4E (0.33) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL457150 | 0.70 | — | — | |
| SCHEMBL12503751 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL15063894 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL457041 | 0.68 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL457040 | 0.68 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15341175 | 0.67 | KDM4E (0.36) | ALDH1A1HPGDMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL457470 | 0.67 | KDM4E (0.40) | ALDH1A1HPGDMAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |