Sugi Predict

Sugi Predict / Compounds / SCHEMBL1028875

SCHEMBL1028875

SCHEMBL1028875

C=C(C)C(=O)Nc1[c]cccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.41
▸ POLB P06746 4/20 0.38
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ GAA P10253 3/20 0.38
▸ RECQL P46063 2/20 0.38
▸ BLM P54132 2/20 0.38
▸ HPGD P15428 3/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ NLRP1 Q9C000 1/20 0.36
▸ NPC1 O15118 3/20 0.36
▸ RAB9A P51151 3/20 0.36
▸ HSD17B10 Q99714 2/20 0.34
▸ NAPRT Q6XQN6 1/20 0.34
▸ MAPT P10636 2/20 0.32
▸ BAZ1A Q9NRL2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482039 0.82 NPC1 (0.32) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL97108 0.81 HSD17B10 (0.48) TDP1ALDH1A1RXFP1POLBL3MBTL1
SCHEMBL3760045 0.79 PTPN1 (0.46) KMT2A
SCHEMBL9725165 0.77 SMN1; SMN2 (0.44) ALDH1A1RECQLKMT2ALMNAHTT
SCHEMBL3760338 0.76 POLB (0.42) KDM4EPOLBGAAKMT2ALMNA
SCHEMBL11124266 0.76 TDP1 (0.57) TDP1ALDH1A1KDM4ERXFP1POLB
SCHEMBL11072074 0.75 SMN1; SMN2 (0.33) ALDH1A1RECQLHSD17B10NAPRT
SCHEMBL6033544 0.75 SMN1; SMN2 (0.38) TDP1ALDH1A1KDM4EPOLBGAA
SCHEMBL3996276 0.74 SMN1; SMN2 (0.53) TDP1ALDH1A1POLBL3MBTL1GAA
SCHEMBL1415961 0.74 SMN1; SMN2 (0.43) ALDH1A1KDM4EPOLBGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
CN-114085391-B High-sensitivity flexible pressure sensing material in pure water and application thereof 天津大学 2022-05-13 — — CN disclosed
CN-114085391-A High-sensitivity flexible pressure sensing material in pure water and application thereof 天津大学 2022-02-25 — — CN disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-02-25 — — US disclosed
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-01-21 — — US disclosed
US-10689348-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2020-06-23 — — US disclosed
US-10435374-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2019-10-08 — — US disclosed
US-9802899-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2017-10-31 — — US disclosed
EP-1928941-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER Nippon Shokubai Co.,Ltd. (JP) 2008-06-11 — — EP disclosed
WO-2007061919-A3 CONTACT LENSES WITH MUCIN AFFINITY BAUSCH & LOMB (US) 2007-11-08 — — WO disclosed
WO-2007061919-A2 CONTACT LENSES WITH MUCIN AFFINITY BAUSCH & LOMB INCORPORATED (US) 2007-05-31 — — WO disclosed
WO-2007037501-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-05 — — WO disclosed
WO-2002046759-A1 DEVICE FOR CAPTURING A TARGET MOLECULE BIO MERIEUX (FR) 2002-06-13 — — WO disclosed
EP-0555460-B1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER OREAL (FR) 1995-05-31 — — EP disclosed
EP-0555460-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER. OREAL (FR) 1993-08-18 — — EP disclosed
WO-1993004666-A1 FILTERING COSMETIC COMPOSITION COMPRISING A NANOPIGMENT OF METAL OXIDE AND A LIPOSOLUBLE FILTER POLYMER L'OREAL (FR) 1993-03-18 — — WO disclosed
US-4719248-A BENZOTRIAZOLE UNSATURATED AMIDE BAUSCH & LOMB INCORPORATED (US) 1988-01-12 — — US disclosed
EP-0221630-A2 Ultraviolet blocking agents for contact lenses BAUSCH & LOMB INCORPORATED (US) 1987-05-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435374-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-10961201-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-10689348-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-11548854-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-11332448-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS TDP1 1836/4885ALDH1A1 2740/4885KDM4E 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.