Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731128 | 0.84 | MPO (0.67) | ALDH1A1TSHRHPGDHSD17B10KMT2A | |
| SCHEMBL16844164 | 0.81 | MPO (0.70) | ALDH1A1HPGDHSD17B10MAPK1XDH | |
| SCHEMBL10288918 | 0.75 | MPO (0.68) | ALDH1A1HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL10288919 | 0.72 | MPO (0.67) | ALDH1A1HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL2731131 | 0.72 | XDH (0.64) | ALDH1A1TSHRHPGDHSD17B10KMT2A | |
| SCHEMBL2730470 | 0.71 | XDH (1.00) | ALDH1A1TSHRHPGDHSD17B10KMT2A | |
| SCHEMBL10289176 | 0.71 | MPO (0.65) | ALDH1A1HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL10288925 | 0.69 | TSHR (0.48) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL15215606 | 0.66 | MPO (0.53) | ALDH1A1TSHRHSD17B10KMT2APKM | |
| SCHEMBL15215605 | 0.65 | MPO (0.55) | ALDH1A1TSHRHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886120-A1 | Quinazoline derivatives, compositions and uses related thereto | Emory University (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2012058211-A2 | QUINAZOLINE DERIVATIVES, COMPOSITIONS, AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2012-05-03 | — | — | WO | disclosed |