SCHEMBL10291360

SCHEMBL10291360

O=C(C1CCC(O)CC1)C(O)C1CCC2OC2C1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
PMP22 Q01453 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
SHBG P04278 1/20 0.32
DPP4 P27487 2/20 0.31
DPP7 Q9UHL4 2/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
PPP5C P53041 2/20 0.30
PPP2CA P67775 1/20 0.30
NPY4R P50391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13315755 0.92 SHBG (0.33) TFPI2KDM4EGMNNLMNAPMP22
SCHEMBL12305109 0.88 KDM4E (0.33) TFPI2KDM4EGMNNLMNAPMP22
SCHEMBL12467720 0.80 DPP4 (0.40) DPP4DPP7
SCHEMBL16559183 0.77 TFPI2 (0.35) TFPI2KDM4EGMNNLMNAPMP22
SCHEMBL3546182 0.72 SHBG (0.35) SHBGDPP4DPP7
SCHEMBL3546702 0.72 SHBG (0.35) SHBGDPP4DPP7
SCHEMBL15727721 0.69 SHBG (0.47) SHBG
SCHEMBL11789675 0.68
SCHEMBL3036355 0.68 KDM4E (0.31) TFPI2KDM4EGMNNLMNAPMP22
SCHEMBL13205863 0.68 SHBG (0.43) SHBGDPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8212471-B2 Light emitting device and electronic equipment provided with the light emitting device SEIKO EPSON CORPORATION (JP) 2012-07-03 US disclosed