Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | CCR8 | P51685 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003787 | 0.94 | SMO (0.60) | SMOEPHX2CCR8 | |
| SCHEMBL10003469 | 0.85 | SMO (0.64) | SMOEPHX2CCR8 | |
| SCHEMBL10003416 | 0.81 | SMO (0.56) | SMOCCR8 | |
| SCHEMBL10003149 | 0.81 | SMO (0.49) | SMOEPHX2CCR8 | |
| SCHEMBL10002932 | 0.80 | MAPT (0.42) | — | |
| SCHEMBL12824618 | 0.80 | SMO (0.50) | SMOEPHX2CCR8 | |
| SCHEMBL10003592 | 0.79 | SMO (0.59) | SMOEPHX2CCR8 | |
| SCHEMBL10003419 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL10002777 | 0.76 | SMO (0.54) | SMOEPHX2 | |
| SCHEMBL12825025 | 0.75 | SMO (0.48) | SMOEPHX2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471789-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-07-04 | — | — | EP | disclosed |