Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 2/20 | 0.36 |
| ▸ | CDK14 | O94921 | 1/20 | 0.36 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12824595 | 0.93 | SMO (0.41) | SMOCCR8EPHX2PHGDHLMNA | |
| SCHEMBL12824618 | 0.87 | SMO (0.50) | SMOCCR8EPHX2CDK14CCNY | |
| SCHEMBL12825070 | 0.87 | NPSR1 (0.39) | CCR8NPSR1 | |
| SCHEMBL16588412 | 0.86 | SMO (0.42) | SMOIRAK4 | |
| SCHEMBL12824871 | 0.86 | SMO (0.52) | SMOCCR8EPHX2LMNAGLA | |
| SCHEMBL10003416 | 0.85 | SMO (0.56) | SMOCCR8LMNAGLAHSD17B10 | |
| SCHEMBL12825027 | 0.85 | SMO (0.43) | SMOEPHX2PHGDHIRAK4 | |
| SCHEMBL12825060 | 0.84 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824860 | 0.84 | CYP2D6 (0.42) | SMOCCR8LMNAGLAHSD17B10 | |
| SCHEMBL12824727 | 0.83 | SMO (0.45) | SMOCCR8EPHX2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |