⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128334 | 0.78 | — | — | |
| SCHEMBL19280 | 0.78 | — | — | |
| SCHEMBL27818201 | 0.76 | — | — | |
| SCHEMBL28740657 | 0.69 | ACHE (0.32) | — | |
| SCHEMBL29074029 | 0.69 | ACHE (0.32) | — | |
| SCHEMBL5466454 | 0.67 | — | — | |
| SCHEMBL6653152 | 0.67 | — | — | |
| SCHEMBL6840967 | 0.67 | — | — | |
| SCHEMBL7548863 | 0.67 | GABRA1 (0.41) | — | |
| SCHEMBL1028797 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | claimed |
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | claimed |
| EP-2566477-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | Glaxo Group Limited (GB) | 2013-03-13 | — | — | EP | claimed |
| US-20130053375-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXO GROUP LIMITED | 2013-02-28 | — | — | US | claimed |
| WO-2011140442-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-11-10 | — | — | WO | claimed |
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | claimed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3986974-B1 | SILICATE BASED HEAT TRANSFER FLUID, METHODS OF ITS PREPARATIONS AND USES THEREOF | ARTECO NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-113214342-B | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| EP-3986974-A1 | SILICATE BASED HEAT TRANSFER FLUID, METHODS OF ITS PREPARATIONS AND USES THEREOF | Arteco NV (BE) | 2022-04-27 | — | — | EP | disclosed |
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | disclosed |
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | disclosed |
| US-4826814-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0298452-A2 | 2H-1-benzopyrane derivatives substituted in position 4 by aryl or N-heteroaryl | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |
| EP-0247464-A1 | New quinolone compounds and a process for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | disclosed |
| EP-0125975-B1 | DIPHENYLAZOMETHINES CARRYING AN ESTERIFIED CHAIN, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SYNTHELABO (FR) | 1986-03-26 | — | — | EP | disclosed |
| EP-0125975-A1 | Diphenylazomethines carrying an esterified chain, their preparation and their therapeutical use | SYNTHELABO (FR) | 1984-11-21 | — | — | EP | disclosed |