SCHEMBL10293950

SCHEMBL10293950

C[N+](C)=c1ccc2c(-c3c(Cl)ccc(Cl)c3C(=O)O)c3ccc(N)cc3oc-2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 5/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MEN1 O00255 4/20 0.43
▸ KMT2A Q03164 4/20 0.43
▸ BLM P54132 2/20 0.43
▸ THRB P10828 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ ABCB1 P08183 1/20 0.41
▸ ATM Q13315 2/20 0.40
▸ CFTR P13569 1/20 0.40
▸ PAX8 Q06710 1/20 0.40
▸ GOPC Q9HD26 1/20 0.40
▸ PARG Q86W56 1/20 0.37
▸ P2RY6 Q15077 1/20 0.36
▸ POLB P06746 3/20 0.36
▸ ALPL P05186 1/20 0.36
▸ ALPI P09923 1/20 0.36
▸ ALPG P10696 1/20 0.36
▸ CA1 P00915 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10293818 0.86 MEN1 (0.62) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL10293814 0.85 ABCB1 (0.54) USP2L3MBTL1MEN1KMT2AABCB1
SCHEMBL10293851 0.84 MEN1 (0.45) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL10293854 0.78 MEN1 (0.35) MEN1KMT2ABLMTHRBRECQL
SCHEMBL12332448 0.76 MEN1 (0.70) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL31488684 0.76 ABCB1 (0.53) USP2L3MBTL1MEN1KMT2AABCB1
SCHEMBL10293845 0.75 MEN1 (0.59) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL14013405 0.73 MEN1 (0.62) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL30291869 0.73 MEN1 (0.56) USP2L3MBTL1MEN1KMT2ABLM
SCHEMBL13015814 0.71 MEN1 (0.61) USP2L3MBTL1MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172583-A1 Oligonucleotides and Analogs Labeled with Energy Transfer Dyes Life Technologies Corporation (US) 2012-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172583-A1 Oligonucleotides and Analogs Labeled with Energy Transfer Dyes RBM28, TRDMT1, RPS28 USP2 4710/4885L3MBTL1 18/4885MEN1 3292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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