SCHEMBL10293845

SCHEMBL10293845

CN(C)c1ccc2c(-c3c(Cl)cc(C(=O)O)c(Cl)c3C(=O)O)c3ccc(=[N+](C)C)cc-3oc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.59
▸ BLM P54132 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ THRB P10828 1/20 0.59
▸ RECQL P46063 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ P2RY6 Q15077 1/20 0.50
▸ CA12 O43570 3/20 0.46
▸ CA1 P00915 3/20 0.46
▸ CA2 P00918 3/20 0.46
▸ CA9 Q16790 3/20 0.46
▸ CA14 Q9ULX7 1/20 0.41
▸ P2RY2 P41231 1/20 0.40
▸ USP2 O75604 2/20 0.40
▸ APAF1 O14727 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ ITPR1 Q14643 1/20 0.40
▸ SLC5A2 P31639 3/20 0.39
▸ GBA1 P04062 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10293818 0.89 MEN1 (0.62) MEN1BLMKMT2ATHRBRECQL
SCHEMBL30291869 0.87 MEN1 (0.56) MEN1BLMKMT2ATHRBRECQL
SCHEMBL10293852 0.86 MEN1 (0.49) MEN1BLMKMT2ATHRBRECQL
Tetramethylrhodamine SCHEMBL2054818 0.81 MEN1 (0.71) MEN1BLMKMT2ATHRBRECQL
SCHEMBL14176750 0.81 MEN1 (0.64) MEN1BLMKMT2ATHRBRECQL
SCHEMBL10293759 0.81 P2RY6 (0.64) MEN1BLMKMT2ATHRBRECQL
SCHEMBL12307301 0.81 MEN1 (0.64) MEN1BLMKMT2ATHRBRECQL
SCHEMBL13024588 0.80 P2RY6 (0.54) P2RY6CA12CA1CA2CA9
SCHEMBL18713197 0.80 MEN1 (0.62) MEN1BLMKMT2ATHRBRECQL
SCHEMBL14013405 0.80 MEN1 (0.62) MEN1BLMKMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172583-A1 Oligonucleotides and Analogs Labeled with Energy Transfer Dyes Life Technologies Corporation (US) 2012-07-05 — — US disclosed
US-20100280246-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE APPLERA CORPORATION (US) 2010-11-04 — — US disclosed
US-7825237-B2 Oligonucleotides and analogs labeled with energy transfer dyes APPLIED BIOSYSTEMS, LLC (US) 2010-11-02 — — US disclosed
US-20100029923-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES Life Technologies Corporation (US) 2010-02-04 — — US disclosed
US-20090118485-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLIED BIOSYSTEMS INC. (US) 2009-05-07 — — US disclosed
US-7452672-B2 Methods of analyzing polynucleotides employing energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-11-18 — — US disclosed
US-7449149-B2 Kits useful for sequencing nucleic acids APPLIED BIOSYSTEMS INC. (US) 2008-11-11 — — US disclosed
US-7449298-B2 Methods of analyzing polynucleotides employing energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-11-11 — — US disclosed
US-7432058-B2 Methods of labeling nucleic acids with energy transfer dyes APPLERA CORPORATION (US) 2008-10-07 — — US disclosed
US-7423140-B2 Oligonucleotides and analogs labeled with energy transfer dyes APPLIED BIOSYSTEMS INC. (US) 2008-09-09 — — US disclosed
US-7388092-B2 Oligonucleotides and analogs labeled with energy transfer dyes APPLERA CORPORATION (US) 2008-06-17 — — US disclosed
US-20070212709-A1 Non-nucleosidic linker linking xanthene donor to 4,7-dichlororhodamine acceptor; APPLERA CORPORATION (US) 2007-09-13 — — US disclosed
US-20070207477-A1 KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS APPLERA CORPORATION (US) 2007-09-06 — — US disclosed
US-20070161026-A1 REGENTS LABELED WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-12 — — US disclosed
US-20070161027-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-12 — — US disclosed
US-20070154927-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-20070154925-A1 METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-20070154924-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-20070154926-A1 Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence APPLERA CORPORATION (US) 2007-07-05 — — US disclosed
US-7169939-B2 Energy transfer dyes with enhanced fluorescence APPLERA CORPORATION (US) 2007-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154924-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RPS28 MEN1 3292/4885BLM 2674/4885KMT2A 1585/4885
US-20100280246-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE SLC25A21, ZCCHC8, ZDHHC7 MEN1 3097/4885BLM 4139/4885KMT2A 1989/4885
US-20100029923-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RPS28 MEN1 3292/4885BLM 2674/4885KMT2A 1585/4885
US-20070212709-A1 Non-nucleosidic linker linking xanthene donor to 4,7-dichlororhodamine acceptor; DCLRE1A, SLC25A21, DIMT1 MEN1 2629/4885BLM 2565/4885KMT2A 1977/4885
US-20070161027-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RTCB MEN1 3323/4885BLM 2619/4885KMT2A 1591/4885
US-20070154926-A1 Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence SLC25A21, RPS28, ZCCHC8 MEN1 3434/4885BLM 3762/4885KMT2A 2147/4885
US-20070161026-A1 REGENTS LABELED WITH ENERGY TRANSFER DYES SOAT1, GFPT1, CBR3 MEN1 2922/4885BLM 2897/4885KMT2A 1151/4885
US-20120172583-A1 Oligonucleotides and Analogs Labeled with Energy Transfer Dyes RBM28, TRDMT1, RPS28 MEN1 3292/4885BLM 2674/4885KMT2A 1585/4885
US-20070207477-A1 KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS RNGTT, POLRMT, MRM1 MEN1 2256/4885BLM 2441/4885KMT2A 1431/4885
US-20090118485-A1 OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES RBM28, TRDMT1, RTCB MEN1 3323/4885BLM 2619/4885KMT2A 1591/4885
US-20070154925-A1 METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES POLRMT, NOP2, NSUN3 MEN1 4042/4885BLM 2522/4885KMT2A 2818/4885
US-20070154927-A1 ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE SLC25A21, ZCCHC8, SLC25A1 MEN1 2922/4885BLM 4079/4885KMT2A 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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