SCHEMBL10295328

SCHEMBL10295328

CN[C@@H]1C=C(CO)[C@H](O)C(O)C1O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGAM O43451 8/20 0.61
SI P14410 6/20 0.61
GLB1 P16278 2/20 0.57
GBA1 P04062 1/20 0.57
TREH O43280 1/20 0.48
AMY2A P04746 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14408655 1.00 MGAM (0.61) MGAMSIGLB1GBA1TREH
SCHEMBL14416125 1.00 MGAM (0.61) MGAMSIGLB1GBA1TREH
SCHEMBL14408591 0.83 MGAM (0.65) MGAMSIGLB1GBA1TREH
SCHEMBL10033385 0.83 MGAM (0.65) MGAMSIGLB1GBA1TREH
SCHEMBL14408753 0.81 MGAM (0.67) MGAMSIGLB1GBA1TREH
SCHEMBL14408748 0.78 MGAM (0.54) MGAMSIGLB1GBA1TREH
SCHEMBL13310709 0.78 MGAM (0.54) MGAMSIGLB1GBA1TREH
SCHEMBL10033383 0.78 MGAM (0.54) MGAMSIGLB1GBA1TREH
SCHEMBL14416329 0.77 MGAM (0.58) MGAMSIGLB1GBA1TREH
SCHEMBL14408740 0.76 MGAM (0.56) MGAMSIGLB1GBA1TREH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211945-B2 Carba-sugar amine derivative and glycolipid metabolic disorder treating agent containing the same as active ingredient SEIKAGAKU CORPORATION (JP) 2012-07-03 US disclosed
US-7790773-B2 Carba-sugar amine derivative and glycolipid metabolic disorder treating agent containing the same as active ingredient SEIKAGAKU CORPORATION (JP) 2010-09-07 US disclosed
US-20090281051-A1 CARBA-SUGAR AMINE DERIVATIVE AND GLYCOLIPID METABOLIC DISORDER TREATING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT SEIKAGAKU CORPORATION (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281051-A1 CARBA-SUGAR AMINE DERIVATIVE AND GLYCOLIPID METABOLIC DISORDER TREATING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT MGLL, GPR119, GLA MGAM 7/4885SI 278/4885GLB1 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.