Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076109 | 0.98 | FDPS (0.41) | FDPSMEN1KMT2ALPOFNTA | |
| Hydrochloric Acid SCHEMBL1028493 | 0.96 | FDPS (0.40) | FDPSMEN1KMT2ALPOFNTA | |
| Hydrochloric Acid SCHEMBL25338116 | 0.96 | FDPS (0.40) | FDPSMEN1KMT2ALPOFNTA | |
| Bromide SCHEMBL38652419 | 0.94 | MAPT (0.41) | FDPSMEN1KMT2ALPOFNTA | |
| SCHEMBL28434335 | 0.91 | FDPS (0.37) | FDPSMEN1KMT2ALPOFNTA | |
| SCHEMBL27576650 | 0.91 | MAPT (0.44) | FDPSMEN1KMT2ALPOFNTA | |
| SCHEMBL659577 | 0.86 | — | — | |
| SCHEMBL2398203 | 0.86 | FDPS (0.46) | FDPSMEN1KMT2ALPOFNTA | |
| SCHEMBL7166348 | 0.86 | FDPS (0.46) | FDPSMEN1KMT2ALPOFNTA | |
| Hydrochloric Acid SCHEMBL28782075 | 0.84 | FDPS (0.42) | FDPSMEN1KMT2ALPOFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110665477-B | Method for preparing molecularly imprinted polymer | 中国农业科学院农业质量标准与检测技术研究所 | 2022-11-22 | — | — | CN | claimed |
| CN-110903433-B | Preparation method of sulfonamide based on aminopropyl-3-methylimidazole and synergist molecularly imprinted polymer thereof | 中国农业科学院农业质量标准与检测技术研究所 | 2021-07-13 | — | — | CN | claimed |
| CN-110903433-A | Preparation method of sulfonamide based on aminopropyl-3-methylimidazole and synergist molecularly imprinted polymer thereof | 中国农业科学院农业质量标准与检测技术研究所 | 2020-03-24 | — | — | CN | claimed |
| CN-110548493-A | Deinking waste newspaper-based adsorbent modified by imidazole ionic liquid and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2019-12-10 | — | — | CN | claimed |
| EP-2152687-B1 | METHOD FOR PRODUCING CARBONATE-TERMINATED COMPOUNDS | SALTIGO GMBH (DE) | 2011-01-19 | — | — | EP | claimed |
| CN-110665477-B | Method for preparing molecularly imprinted polymer | 中国农业科学院农业质量标准与检测技术研究所 | 2022-11-22 | — | — | CN | disclosed |
| CN-110665477-B | Method for preparing molecularly imprinted polymer | 中国农业科学院农业质量标准与检测技术研究所 | 2022-11-22 | — | — | CN | disclosed |
| CN-110903433-B | Preparation method of sulfonamide based on aminopropyl-3-methylimidazole and synergist molecularly imprinted polymer thereof | 中国农业科学院农业质量标准与检测技术研究所 | 2021-07-13 | — | — | CN | disclosed |
| CN-113072916-A | Modified graphene-based heat conduction enhanced ionic liquid composite phase change heat storage material and preparation method thereof | 西安交通大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110903433-A | Preparation method of sulfonamide based on aminopropyl-3-methylimidazole and synergist molecularly imprinted polymer thereof | 中国农业科学院农业质量标准与检测技术研究所 | 2020-03-24 | — | — | CN | disclosed |
| CN-110665477-A | Method for preparing molecularly imprinted polymer | 中国农业科学院农业质量标准与检测技术研究所 | 2020-01-10 | — | — | CN | disclosed |
| CN-110548493-A | Deinking waste newspaper-based adsorbent modified by imidazole ionic liquid and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2019-12-10 | — | — | CN | disclosed |
| CN-110548493-A | Deinking waste newspaper-based adsorbent modified by imidazole ionic liquid and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2019-12-10 | — | — | CN | disclosed |
| CN-103977839-B | A kind of ionic organic metal tungstates epoxidation catalyst and preparation method thereof | JIANGNAN UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-103977839-A | Ionic organic metal tungstate epoxidation catalyst and preparation method thereof | UNIV JIANGNAN | 2014-08-13 | — | — | CN | disclosed |