⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23361037 | 0.98 | FDPS (0.42) | — | |
| Hydrochloric Acid SCHEMBL28782075 | 0.98 | FDPS (0.42) | — | |
| SCHEMBL31276947 | 0.92 | FDPS (0.39) | — | |
| SCHEMBL19212948 | 0.89 | CNR2 (0.39) | — | |
| SCHEMBL1076109 | 0.88 | FDPS (0.41) | — | |
| SCHEMBL7154948 | 0.86 | FDPS (0.48) | — | |
| Bromide SCHEMBL1029607 | 0.86 | FDPS (0.40) | — | |
| Hydrochloric Acid SCHEMBL1028493 | 0.86 | FDPS (0.40) | — | |
| Hydrochloric Acid SCHEMBL25338116 | 0.86 | FDPS (0.40) | — | |
| SCHEMBL27576650 | 0.84 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639357-B2 | Dihydrochromene derivatives | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-02 | — | — | US | disclosed |
| CN-112313274-B | Crosslinkable nitrile rubber composition and crosslinked rubber | 日本瑞翁株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-110461892-B | Nitrile group-containing copolymer rubber | 日本瑞翁株式会社 | 2022-02-11 | — | — | CN | disclosed |
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| EP-3770162-A1 | DIHYDROCHROMENE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-01-27 | — | — | EP | disclosed |
| US-20210002290-A1 | DIHYDROCHROMENE DERIVATIVES | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| US-10807993-B2 | Dihydrochromene derivatives | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-20 | — | — | US | disclosed |
| US-20200216461-A1 | DIHYDROCHROMENE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |
| WO-2009140517-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| WO-2009002933-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009002933-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| US-20080132526-A1 | Purine Derivative | GLAXO GROUP LIMITED (GB) | 2008-06-05 | — | — | US | disclosed |
| WO-2007059949-A1 | TWO NOVEL SALTS OF THE N, N' -BIS [9- (3,4-DIHYDROXY-5- (2-ETHYL-2H-TETRAZOL-5-YL) TETRAHYDROFURAN-2-YL) -2- (2- (1-METHYL-1H-IMIDAZOL-4-YL) ETHYLAMINO) -9H-PURIN-6-YL] CYCLOHEXYL-1,4-DIAMINE ADENOSINE A2A AGONIST AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2007-05-31 | — | — | WO | disclosed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |