Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106404 | 0.83 | RORC (0.39) | RORCLIPG | |
| SCHEMBL106403 | 0.83 | RORC (0.39) | RORCLIPG | |
| SCHEMBL168097 | 0.82 | SLC2A1 (0.44) | RORC | |
| SCHEMBL168096 | 0.82 | SLC2A1 (0.44) | RORC | |
| SCHEMBL3592710 | 0.80 | GRM5 (0.41) | RORC | |
| SCHEMBL103414 | 0.80 | GRM5 (0.41) | RORC | |
| SCHEMBL138523 | 0.80 | HTR1A (0.41) | RORCNR1I2 | |
| SCHEMBL138524 | 0.80 | HTR1A (0.41) | RORCNR1I2 | |
| SCHEMBL103873 | 0.76 | SMARCA2 (0.43) | RORC | |
| SCHEMBL103871 | 0.76 | SMARCA2 (0.43) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |