SCHEMBL10299

SCHEMBL10299

c1cnc2sccc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30337062 1.00
SCHEMBL3604842 0.98 LMNA (0.42)
SCHEMBL3608596 0.98 LMNA (0.42)
Hydrogen Sulfide SCHEMBL3608592 0.98 LMNA (0.42)
SCHEMBL8166280 0.80 KMT2A (0.35)
Trifluoromethanesulfonic Acid SCHEMBL27315493 0.80 KDM4E (0.42)
SCHEMBL30060147 0.79
SCHEMBL5884137 0.79 ALDH1A1 (0.37)
SCHEMBL23218293 0.72 KDM4E (0.58)
Quinoline SCHEMBL9486661 0.69 ALDH1A1 (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2826 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
EP-4658655-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US claimed
US-12465604-B2 Functional cure of retroviral infection KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-11-11 US claimed
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS ROCHE SEQUENCING SOLUTIONS INC (US) 2025-03-06 US claimed
CN-119552174-A TLR7 and TLR8 inhibitors, methods of making, pharmaceutical compositions and uses thereof 上海深势唯思科技有限责任公司 2025-03-04 CN claimed
CN-115103835-B IL-17A modulators and uses thereof 戴斯阿尔法公司 2024-12-10 CN claimed
WO-2024160276-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
WO-2024160278-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
EP-0628562-A1 Cephalospornis having in position 7 as substituted axymino radical, intermediates, processes for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1994-12-14 EP claimed
CN-1096298-A Contain the novel cephalosporin of the oxyimino group of replacement, their preparation method and intermediate on seven and as the purposes of medicine ROUSSEL UCLAF (FR) 1994-12-14 CN claimed
EP-0236880-B1 Penem derivatives ERBA CARLO SPA (IT) 1994-07-20 EP claimed
EP-0551034-A2 Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1993-07-14 EP claimed
CN-1073177-A Novel cephalosporins containing a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1993-06-16 CN claimed
US-4886793-A PENICILLINS; HUMANS OR ANIMALS FARMITALIA CARLO ERBA, S.R.L. (IT) 1989-12-12 US claimed
EP-0236880-A2 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1987-09-16 EP claimed
US-4406898-A ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP ELI LILLY AND COMPANY (US) 1983-09-27 US claimed
EP-0003645-B1 PROCESS FOR THE PREPARATION OF AROMATIC (B)-FUSED PYRIDINES AND NOVEL THIENO(B)PYRIDINES CRODA SYNTHETIC CHEMICALS LIMITED (GB) 1982-05-05 EP claimed
EP-0003645-A1 Process for the preparation of aromatic (b)-fused pyridines and novel thieno(b)pyridines CRODA SYNTHETIC CHEMICALS LIMITED (GB) 1979-08-22 EP claimed