⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956118 | 0.76 | TSHR (0.50) | — | |
| SCHEMBL28335 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL4593032 | 0.69 | — | — | |
| SCHEMBL28864996 | 0.69 | — | — | |
| SCHEMBL27739687 | 0.69 | — | — | |
| SCHEMBL3066659 | 0.69 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL9736295 | 0.69 | — | — | |
| SCHEMBL6124940 | 0.69 | — | — | |
| Fluoride SCHEMBL11220083 | 0.69 | — | — | |
| SCHEMBL28009988 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102149543-B | Deoxygenating laminate | MITSUBISHI GAS CHEMICAL CO | 2014-09-03 | — | — | CN | disclosed |
| CN-102131641-B | Deoxidizing multilayered body | MITSUBISHI GAS CHEMICAL CO | 2013-11-13 | — | — | CN | disclosed |
| US-20130018054-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2013-01-17 | — | — | US | disclosed |
| US-20130018074-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2013-01-17 | — | — | US | disclosed |
| US-8217065-B2 | Organic compounds | NOVARTIS AG (SE) | 2012-07-10 | — | — | US | disclosed |
| CN-102149543-A | Deoxygenating laminate | MITSUBISHI GAS CHEMICAL CO | 2011-08-10 | — | — | CN | disclosed |
| CN-102131641-A | Deoxidizing multilayered body | MITSUBISHI GAS CHEMICAL CO | 2011-07-20 | — | — | CN | disclosed |
| US-20110077277-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2011-03-31 | — | — | US | disclosed |
| US-7879850-B2 | such as 6-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-2-(2,6-dichloro-phenyl)-1H-benzoimidazole, having diacylglycerol O-acyl transferase inhibitory activity, used for the treatment of impaired glucose tolerance, non-insulin dependent diabetes or obesity | NOVARTIS AG (CH) | 2011-02-01 | — | — | US | disclosed |
| US-20090247534-A1 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2009-10-01 | — | — | US | disclosed |
| US-20090186891-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-07-23 | — | — | US | disclosed |
| WO-2009040410-A1 | OXADIAZOLE- AND OXAZOLE-SUBSTITUTED BENZIMIDAZOLE- AND INDOLE-DERIVATIVES AS DGAT1 INHIBITORS | NOVARTIS AG (CH) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | disclosed |