Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL4593032 | 0.92 | — | — | |
| SCHEMBL28009988 | 0.92 | — | — | |
| SCHEMBL27739687 | 0.92 | — | — | |
| Fluoride SCHEMBL11220083 | 0.92 | — | — | |
| SCHEMBL28864996 | 0.92 | — | — | |
| SCHEMBL27826196 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL114313 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28021510 | 0.77 | CA2 (0.54) | — | |
| Hydrochloric Acid SCHEMBL15847854 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108120787-A | The qualitative-and-quantitative method of antioxidant in polyolefin | 上海微谱化工技术服务有限公司 | 2018-06-05 | — | — | CN | claimed |
| WO-2024002210-A1 | AROMATIC AMIDE DERIVATIVE AND USE THEREOF IN ANTITUMOR DRUGS | 上海喆邺生物科技有限公司 | 2024-01-04 | — | — | WO | disclosed |
| CN-110088102-A | A kind of nitrogen-containing hetero cyclics, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110088101-A | A kind of nitrogen-containing hetero cyclics, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106132968-B | Bromodomain-inhibiting compound for preventing or treating cancer and pharmaceutical composition containing the same | 康佳诺医疗科技发展有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-108120787-A | The qualitative-and-quantitative method of antioxidant in polyolefin | 上海微谱化工技术服务有限公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-107954999-A | Han oxadiazole rings compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-107801378-A | PlX-8394 or P L X-7904 for the treatment of BRAF-V600 related diseases | 普莱希科公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-107382796-A | A kind of series antineoplastic medicaments of CA 4, synthetic method and its application | 上海应用技术大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-106565696-A | Oxadiazole derivative, preparing method of oxadiazole derivative and application of oxadiazole derivative to medicines | 江苏恒瑞医药股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106543188-A | A kind of amino tetrahydro pyran derivant and its purposes in medicine | 成都融科博海科技有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-106132968-A | Bromodomain-inhibiting compound for preventing or treating cancer and pharmaceutical composition containing the same | 康佳诺医疗科技发展有限公司 | 2016-11-16 | — | — | CN | disclosed |
| US-5128371-A | Acylated naphthlamines as plant fungicides | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| CN-1054421-A | 3- (substituted phenyl) pyrazole derivatives, salts thereof, herbicides prepared therefrom and process for preparing said derivatives or salts | NIHON NOHYAKU CO LTD (JP) | 1991-09-11 | — | — | CN | disclosed |
| US-4327034-A | CHEMICAL INTERMEDIATE PREPARED FROM A SULFAMIC ACID HALIDE AND A HALOGEN COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| EP-0001266-A1 | Substituted 2-aminomethylphenyl sulfamates, process for preparing, and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4096181-A | Substituted sulfamic acid halides | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-4049709-A | Vinyl-substituted sulfamic acid halides | BASF AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |