Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092743 | 0.98 | SPHK2 (0.34) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL13864353 | 0.90 | SPHK2 (0.32) | TSHRSPHK2SPHK1 | |
| SCHEMBL27805429 | 0.83 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2467574 | 0.81 | KMT2A (0.48) | TSHRMAPTALOX15CES2 | |
| SCHEMBL16038174 | 0.81 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL6037734 | 0.81 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6884845 | 0.81 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL4664635 | 0.81 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL14416895 | 0.81 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL50896 | 0.81 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263972-B2 | Organic electroluminescent device and display medium | FUJI XEROX CO. LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8263972-B2 | Organic electroluminescent device and display medium | FUJI XEROX CO. LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8217391-B2 | Organic semiconductor transistor, method of producing the same, and electronic device | FUJI XEROX CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8217391-B2 | Organic semiconductor transistor, method of producing the same, and electronic device | FUJI XEROX CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100276672-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100276672-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-7812172-B2 | Charge transport materials; for organic electronic devices such as organic photoreceptors, organic electroluminescence devices, organic transistors, and organic optical memories | FUJI XEROX CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-7812172-B2 | Charge transport materials; for organic electronic devices such as organic photoreceptors, organic electroluminescence devices, organic transistors, and organic optical memories | FUJI XEROX CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20100243995-A1 | ORGANIC SEMICONDUCTOR TRANSISTOR, METHOD OF PRODUCING THE SAME, AND ELECTRONIC DEVICE | FUJI XEROX CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100243995-A1 | ORGANIC SEMICONDUCTOR TRANSISTOR, METHOD OF PRODUCING THE SAME, AND ELECTRONIC DEVICE | FUJI XEROX CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| WO-2009064975-A1 | QUINOXALINE-CONTAINING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100276672-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY MEDIUM | L1CAM, OR10J3, ALK | TSHR 1934/4885THRB 1437/4885SPHK2 4545/4885 |
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | BCAT1, ABAT, BCAT2 | TSHR 342/4885THRB 335/4885SPHK2 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.