Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9133478 | 1.00 | MEN1 (0.55) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL32677450 | 0.99 | MEN1 (0.54) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL16166943 | 0.99 | MEN1 (0.54) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14815769 | 0.99 | MEN1 (0.52) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Fluoride Ion SCHEMBL14815771 | 0.97 | MEN1 (0.51) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL14815770 | 0.97 | MEN1 (0.51) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Iodide SCHEMBL14815646 | 0.97 | MEN1 (0.51) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3899764 | 0.95 | MEN1 (0.50) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| SCHEMBL7917382 | 0.95 | MEN1 (0.50) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Fluoride Ion SCHEMBL14815193 | 0.93 | MEN1 (0.49) | MEN1KMT2ATP53MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156772-B2 | Fluoride-releasing compositions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-13 | — | — | US | disclosed |
| US-20140088308-A1 | Fluoride-Releasing Compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2014-03-27 | — | — | US | disclosed |
| US-20120264939-A1 | Fluoride-Releasing Compositions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-10-18 | — | — | US | disclosed |
| US-20120264939-A1 | Fluoride-Releasing Compositions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-10-18 | — | — | US | disclosed |
| US-8217173-B2 | Fluoride-releasing compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217173-B2 | Fluoride-releasing compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2012-07-10 | — | — | US | disclosed |
| US-20100261902-A1 | Fluoride-Releasing Compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100261902-A1 | Fluoride-Releasing Compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088308-A1 | Fluoride-Releasing Compositions | CHERP, ORAI1, CAD | MEN1 1176/4885KMT2A 3397/4885TP53 3925/4885 |
| US-20120264939-A1 | Fluoride-Releasing Compositions | CHERP, ORAI1, CAD | MEN1 1176/4885KMT2A 3397/4885TP53 3925/4885 |
| US-20100261902-A1 | Fluoride-Releasing Compositions | CHERP, ORAI1, CAD | MEN1 1176/4885KMT2A 3397/4885TP53 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.