Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823353 | 0.93 | FAAH (0.40) | FFAR1PTGS2PTGS1MRGPRX4FAAH | |
| SCHEMBL12823294 | 0.89 | FFAR1 (0.45) | FFAR1PTGS2MRGPRX4FFAR4PPARD | |
| SCHEMBL10303127 | 0.88 | MRGPRX4 (0.37) | FFAR1PTGS2MRGPRX4FFAR4KDM4E | |
| SCHEMBL10303179 | 0.88 | FFAR1 (0.40) | FFAR1PTGS2PTGS1MRGPRX4FAAH | |
| SCHEMBL13586331 | 0.87 | FFAR1 (0.45) | FFAR1FAAHPPARD | |
| SCHEMBL10303140 | 0.87 | MRGPRX4 (0.36) | FFAR1PTGS2PTGS1MRGPRX4FFAR4 | |
| SCHEMBL10302880 | 0.84 | MAPT (0.39) | FFAR4KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL10302275 | 0.84 | S1PR1 (0.42) | FFAR1FFAR4PPARDNPC1HPGD | |
| SCHEMBL10303067 | 0.84 | PTGS2 (0.39) | PTGS2PTGS1FAAHFFAR4PPARD | |
| SCHEMBL13586388 | 0.84 | FAAH (0.42) | FFAR1FAAHFFAR4PPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216489-B2 | Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |