Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728883 | 0.91 | HRH1 (0.47) | SLC6A2HTR1AACHEFAAHMGLL | |
| SCHEMBL632508 | 0.75 | ACHE (0.41) | HTR1ASSTR4ACHEFAAHMGLL | |
| SCHEMBL8371387 | 0.75 | FAAH (0.41) | SSTR4ACHEFAAHMGLL | |
| SCHEMBL911841 | 0.75 | SLC6A4 (0.44) | SLC6A2ACHEFAAHMGLL | |
| SCHEMBL911842 | 0.75 | SLC6A4 (0.44) | SLC6A2ACHEFAAHMGLL | |
| SCHEMBL7278648 | 0.74 | ACHE (0.45) | SLC6A2HTR1AACHEFAAHMGLL | |
| SCHEMBL9411204 | 0.73 | ACHE (0.62) | SLC6A2SSTR4ACHEFAAHMGLL | |
| Hydrochloric Acid SCHEMBL7280360 | 0.73 | ACHE (0.44) | SLC6A2HTR1AACHEFAAHMGLL | |
| SCHEMBL632513 | 0.73 | ACHE (0.39) | SSTR4ACHEFAAHMGLL | |
| SCHEMBL8374400 | 0.73 | SSTR4 (0.38) | SSTR4ACHEFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863793-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-04 | — | — | EP | disclosed |
| WO-2008057871-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2007056120-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |