⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28300406 | 0.77 | NOS3 (0.52) | — | |
| SCHEMBL172774 | 0.77 | — | — | |
| SCHEMBL762583 | 0.77 | — | — | |
| SCHEMBL14303617 | 0.74 | — | — | |
| SCHEMBL30702055 | 0.73 | — | — | |
| SCHEMBL22576156 | 0.73 | — | — | |
| SCHEMBL30230776 | 0.73 | — | — | |
| SCHEMBL305800 | 0.73 | — | — | |
| SCHEMBL221321 | 0.73 | — | — | |
| SCHEMBL845972 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474532-A1 | Heteroaryl sulfonamides and CCR2 | ChemoCentryx, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-1838674-B9 | HETEROARYL SULFONAMIDES AND CCR2 | CHEMOCENTRYX INC (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-2354126-A1 | Heteroaryl sulfonamides and CCR2 | ChemoCentryx, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |
| EP-1838674-B1 | HETEROARYL SULFONAMIDES AND CCR2 | CHEMOCENTRYX INC (US) | 2011-03-30 | — | — | EP | disclosed |