SCHEMBL845972

SCHEMBL845972

Cc1cnc(O)c(N)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172774 0.75
SCHEMBL762583 0.75
SCHEMBL6629858 0.75
SCHEMBL12420722 0.75
SCHEMBL13514472 0.75
SCHEMBL28300406 0.75 NOS3 (0.52)
SCHEMBL10305656 0.73
SCHEMBL18914210 0.73
SCHEMBL14038065 0.71 KDM4E (0.38)
SCHEMBL618186 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437463-B Dendritic polymer, preparation method and application thereof 威海晨源分子新材料有限公司 2022-01-21 CN claimed
CN-106366310-B Carboxyl-containing high-refractive-index hyperbranched polyesteramide, preparation method thereof and application thereof in plastic modification 威海晨源分子新材料有限公司 2020-09-08 CN claimed
CN-117945570-B Low-cost and low-energy consumption treatment process for acrylonitrile device wastewater 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-117985873-A Process for treating wastewater of acrylonitrile device 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-117964133-A Low-salt treatment process for acrylonitrile device wastewater 中国石油化工股份有限公司 2024-05-03 CN disclosed
CN-117945570-A Low-cost and low-energy consumption treatment process for acrylonitrile device wastewater 中国石油化工股份有限公司 2024-04-30 CN disclosed
EP-4265607-A1 AMINOPYRIDINE COMPOUND AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2023-10-25 EP disclosed
CN-110105300-B Method for synthesizing 2-trifluoroethyl substituted benzoxazole compound 福州大学 2023-04-14 CN disclosed
CN-110437463-B Dendritic polymer, preparation method and application thereof 威海晨源分子新材料有限公司 2022-01-21 CN disclosed
CN-106366310-B Carboxyl-containing high-refractive-index hyperbranched polyesteramide, preparation method thereof and application thereof in plastic modification 威海晨源分子新材料有限公司 2020-09-08 CN disclosed
US-20180002347-A1 CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2018-01-04 US disclosed
US-20110028467-A1 HETEROCYCLIC DERIVATIVES C&C RESEARCH LABORATORIES (KR) 2011-02-03 US disclosed
US-7879845-B2 Liver carnitine-dependent palmitoyltransferase (L-CPT1) inhibitors such as 4-{[4-(5-Chloro-2-methoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-6-carbonyl]-amino}-benzoic acid, used for the treatment of non-insulin dependent diabetes; antidiabetic agents HOFFMANN-LA ROCHE INC. (US) 2011-02-01 US disclosed
EP-2266989-A2 HETEROCYCLIC DERIVATIVES C&c Research Laboratories (KR) 2010-12-29 EP disclosed
US-20100298334-A1 N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS INCYTE CORPORATION 2010-11-25 US disclosed
US-20100130484-A1 NOVEL BICYCLIC SULFONAMIDE DERIVATIVES WHICH ARE L-CPT1 INHIBITORS ACKERMANN JEAN 2010-05-27 US disclosed
US-7696200-B2 Bicyclic sulfonamide derivatives which are L-CPT1 inhibitors HOFFMANN-LA ROCHE INC. (US) 2010-04-13 US disclosed
WO-2007147782-A2 OXIME SULFONATES AND THE USE THEROF AS LATENT ACIDS CIBA HOLDING INC. (CH) 2007-12-27 WO disclosed
US-20070191603-A1 Novel bicyclic sulfonamide derivatives which are L-CPT1 inhibitors F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) 2007-08-16 US disclosed
US-3935195-A FLUORESCENT DYE STERLING DRUG INC. (US) 1976-01-27 US disclosed