SCHEMBL10307337

SCHEMBL10307337

CC(=O)c1cncc(C)n1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 5/20 0.46
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
FPR2 P25090 3/20 0.34
KDM4E B2RXH2 3/20 0.33
HCAR2 Q8TDS4 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.33
P2RX7 Q99572 1/20 0.33
PSMB5 P28074 1/20 0.33
NAPRT Q6XQN6 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
NTRK1 P04629 1/20 0.31
CBLB Q13191 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498786 1.00 GRM5 (0.46) GRM5SMN1; SMN2ALDH1A1POLBFPR2
SCHEMBL16310786 0.85 ALDH1A1 (0.39) GRM5SMN1; SMN2ALDH1A1KDM4EHCAR2
SCHEMBL287705 0.82 GRM5 (0.46) GRM5SMN1; SMN2ALDH1A1KDM4EHCAR2
SCHEMBL22711336 0.80 GRM5 (0.49) GRM5SMN1; SMN2ALDH1A1FPR2KDM4E
SCHEMBL3743154 0.80 ADORA3 (0.47) GRM5POLBP2RX7
SCHEMBL28215838 0.80 GRM5 (0.45) GRM5SMN1; SMN2ALDH1A1FPR2KDM4E
Hydrochloric Acid SCHEMBL2673698 0.78 ADORA3 (0.45) GRM5POLBP2RX7
SCHEMBL27315955 0.77 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1KDM4EHCAR2NAPRT
SCHEMBL12094161 0.77 ATM (0.47) GRM5SMN1; SMN2ALDH1A1KDM4ENPC1
SCHEMBL30419529 0.77 ATM (0.47) GRM5SMN1; SMN2ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113219072-B Method for identifying and analyzing key flavor components in colored sugar 中粮集团有限公司 2023-10-27 CN claimed
US-11013250-B2 Methods and compositions for consumables IMPOSSIBLE FOODS INC. (US) 2021-05-25 US claimed
US-10993462-B2 Methods and compositions for consumables IMPOSSIBLE FOODS INC. (US) 2021-05-04 US claimed
CN-111575106-A Sesame oil squeezing method and equipment and prepared sesame oil 青岛嘉里花生油有限公司 2020-08-25 CN claimed
CN-105779108-B Sesame oil squeezing method and equipment and prepared sesame oil 青岛嘉里花生油有限公司 2020-06-30 CN claimed
US-20190200658-A1 METHODS AND COMPOSITIONS FOR CONSUMABLES IMPOSSIBLE FOODS INC. 2019-07-04 US claimed
US-20190116855-A1 METHODS AND COMPOSITIONS FOR CONSUMABLES IMPOSSIBLE FOODS INC. 2019-04-25 US claimed
US-20240298680-A1 METHODS AND COMPOSITIONS FOR CONSUMABLES IMPOSSIBLE FOODS INC. 2024-09-12 US disclosed
CN-113219072-B Method for identifying and analyzing key flavor components in colored sugar 中粮集团有限公司 2023-10-27 CN disclosed
EP-4205565-A1 TOBACCO FILLING MATERIAL AND TOBACCO PRODUCT Japan Tobacco Inc. (JP) 2023-07-05 EP disclosed
WO-2023076218-A1 SPIROTRICYCLE RIPK1 INHIBITORS AND METHODS OF USES THEREOF MERCK SHARP & DOHME LLC (US) 2023-05-04 WO disclosed
WO-2023288257-A2 BIOCATALYTIC COUPLING REACTIONS TOWARD REGIOSELECTIVELY ENRICHED SUBSTITUTED PYRAZINES CONAGEN INC. (US) 2023-01-19 WO disclosed
CN-108203617-B Sesame oil and preparation method thereof 丰益(上海)生物技术研发中心有限公司 2022-04-12 CN disclosed
US-4083373-A FLAVOR, AROMA INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-04-11 US disclosed
US-4071535-A 2-Alkyl-4-phenyl-dihydropyrans and processes for augmenting the organoleptic properties of foodstuffs and tobacco using one or more of said pyrans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-31 US disclosed
US-4071034-A 2-Alkyl-4-phenyl-dihydropyrans and processes for augmenting the organoleptic properties of tobacco using one or more of said pyrans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-31 US disclosed
US-4070491-A 2-Alkyl-4-phenyl-dihydropyrans and processes for augmenting the organoleptic properties of foodstuffs and tobacco using one or more of said pyrans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-24 US disclosed
US-4067344-A Novel tobacco product comprising one or more thiazolines and process INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-10 US disclosed
US-3977419-A TOBACCO ARTICLE COMPRISING A FLAVORING COMPOSITION SELECTED FROM BUTANONE DERIVATIVES AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed
US-3977418-A TOBACCO ARTICLE COMPRISING THE FLAVORING COMPOSITION TRICYCLENE-9-BUTENONE AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed