Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031481 | 0.84 | THRB (0.53) | CNR1CNR2FAAHGLALMNA | |
| SCHEMBL1031690 | 0.82 | HPGD (0.46) | CNR1CNR2FAAHALDH1A1HPGD | |
| SCHEMBL2637247 | 0.82 | CHRM1 (0.47) | CNR1CNR2FAAHKDM4EALDH1A1 | |
| SCHEMBL1032507 | 0.80 | PPARG (0.49) | CNR1CNR2FAAHKDM4EALDH1A1 | |
| SCHEMBL1032474 | 0.80 | NPC1 (0.44) | ALDH1A1HPGDLMNATP53MEN1 | |
| SCHEMBL1028497 | 0.79 | PRKAA2 (0.44) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1031104 | 0.79 | CNR1 (0.43) | CNR1CNR2FAAHKDM4EALDH1A1 | |
| SCHEMBL1030364 | 0.79 | MCHR1 (0.47) | CNR1CNR2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL1032118 | 0.79 | POLB (0.40) | CNR1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL1029726 | 0.77 | PTGS2 (0.52) | MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |