Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310398 | 0.98 | MAPT (0.38) | MAPTHPGDNPC1SMN1; SMN2HTT | |
| SCHEMBL10310392 | 0.91 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL12941128 | 0.68 | MAPT (0.32) | MAPTHPGDNPC1SMN1; SMN2HTT | |
| SCHEMBL10310418 | 0.67 | — | — | |
| SCHEMBL10310423 | 0.65 | — | — | |
| SCHEMBL3083745 | 0.65 | MAPT (0.49) | MAPTHPGDNPC1SMN1; SMN2HTT | |
| SCHEMBL7699680 | 0.63 | MAPT (0.40) | MAPTHPGDNPC1SMN1; SMN2HTT | |
| SCHEMBL4438245 | 0.60 | APOBEC3A (0.39) | MAPTHPGDSMN1; SMN2HTTLMNA | |
| SCHEMBL8339210 | 0.60 | MAPT (0.47) | MAPTHPGDNPC1SMN1; SMN2HTT | |
| SCHEMBL4747481 | 0.58 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805938-A1 | Bi- or tricyclic sterically hindered alkoxyamines and process for their preparation | BASF SE (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8809533-B2 | Bi- or tricyclic sterically hindered alkoxyamines and process for their preparation | BASF SE (DE) | 2014-08-19 | — | — | US | disclosed |
| US-8809533-B2 | Bi- or tricyclic sterically hindered alkoxyamines and process for their preparation | BASF SE (DE) | 2014-08-19 | — | — | US | disclosed |
| EP-2464628-B1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-20140039100-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2014-02-06 | — | — | US | disclosed |
| US-20140039100-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2014-02-06 | — | — | US | disclosed |
| US-20120178829-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178829-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2012-07-12 | — | — | US | disclosed |
| WO-2011018384-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | BASF SE (DE) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178829-A1 | BI - OR TRICYCLIC STERICALLY HINDERED ALKOXYAMINES AND PROCESS FOR THEIR PREPARATION | CAT, SCO2, GPX4 | MAPT 1125/4885HPGD 4085/4885NPC1 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.