Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402038 | 0.85 | HRH3 (0.46) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL10311540 | 0.84 | HRH3 (0.44) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL11957133 | 0.81 | HRH3 (0.37) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL10311533 | 0.78 | HRH3 (0.40) | HRH3CYP3A4KDM4ERECQLTDP1 | |
| SCHEMBL10311586 | 0.78 | HRH3 (0.42) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL9345230 | 0.78 | HRH3 (0.50) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL9345250 | 0.78 | HRH3 (0.50) | HRH3RAB9ACYP2C9KCNH2CYP3A4 | |
| SCHEMBL10311577 | 0.77 | RARB (0.39) | HRH3RAB9ACYP2C9CYP3A4 | |
| SCHEMBL10311516 | 0.77 | ESR2 (0.39) | HRH3ESR2 | |
| SCHEMBL10311460 | 0.76 | ESR2 (0.45) | HRH3ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |