Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402075 | 0.86 | MEN1 (0.48) | HRH3MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10311610 | 0.84 | KDM4E (0.43) | HRH3TDP1KDM4ERECQL | |
| SCHEMBL10311549 | 0.83 | KDM4E (0.34) | HRH3MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10311588 | 0.83 | KDM4E (0.36) | HRH3MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL10311540 | 0.79 | HRH3 (0.44) | HRH3CYP3A4TDP1KDM4ERECQL | |
| SCHEMBL10311425 | 0.78 | ITGB3 (0.40) | HRH3MEN1USP2ALDH1A1LMNA | |
| SCHEMBL13402067 | 0.78 | KDM4E (0.43) | HRH3MEN1KMT2ATDP1KDM4E | |
| SCHEMBL10311524 | 0.78 | HRH3 (0.37) | HRH3CYP3A4TDP1KDM4ERECQL | |
| SCHEMBL10311456 | 0.78 | NR5A1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL10311471 | 0.75 | TP53 (0.33) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |