SCHEMBL1031176

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034595	0.90	SMN1; SMN2 (0.42)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL1030011	0.89	PIM1 (0.43)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL1033053	0.89	ALDH1A1 (0.45)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL17772320	0.89	NPC1 (0.47)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL1029976	0.88	MEN1 (0.43)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL1034502	0.88	PIM1 (0.48)	NPC1RAB9AMEN1KMT2AKDR
	SCHEMBL1034649	0.88	PIM1 (0.42)	MEN1KMT2APIM1KMOATR
	SCHEMBL1031894	0.86	MAPT (0.41)	NPC1RAB9AMEN1KMT2APIM1
	SCHEMBL1033961	0.86	PRKDC (0.41)	PIM1THRBSMN1; SMN2ALDH1A1HPGD
	SCHEMBL1034277	0.86	PIM1 (0.41)	MEN1KMT2AKDRPIM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.