SCHEMBL1031187

SCHEMBL1031187

C=C[C@H]1[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)c2c(O)cc(O)cc2-c2cccc(O)c2)OC=C2C(=O)OCC[C@H]21

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.61
▸ EPHX2 P34913 3/20 0.38
▸ KDM4E B2RXH2 3/20 0.34
▸ POLB P06746 2/20 0.34
▸ GAA P10253 2/20 0.34
▸ APEX1 P27695 2/20 0.34
▸ HSP90AA1 P07900 2/20 0.34
▸ MAPT P10636 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ SLC28A3 Q9HAS3 3/20 0.33
▸ XDH P47989 1/20 0.32
▸ P4HB P07237 2/20 0.32
▸ ACHE P22303 1/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ AKR1B1 P15121 1/20 0.32
▸ CA4 P22748 1/20 0.32
▸ CA7 P43166 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22662483 1.00 STAT3 (0.61) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL22662484 1.00 STAT3 (0.61) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL29655170 0.95 STAT3 (0.61) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL10307294 0.91 STAT3 (0.49) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL10307500 0.84 STAT3 (0.39) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL29655256 0.83 STAT3 (0.39) STAT3EPHX2KDM4EPOLBGAA
SCHEMBL22645247 0.83 STAT3 (0.59) STAT3KDM4EAPEX1MAPTRECQL
SCHEMBL13998188 0.81 STAT3 (0.43) STAT3
SCHEMBL29425739 0.79 STAT3 (0.69) STAT3GAAHSP90AA1SLC28A3CA12
SCHEMBL29655347 0.78 STAT3 (0.67) STAT3KDM4EHSP90AA1XDHCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 — — EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 — — US claimed
EP-4561377-B1 AEROSOL-GENERATING ARTICLE WITH EMBEDDED AVERSIVE AGENT PHILIP MORRIS PRODUCTS SA (CH) 2026-03-25 — — EP claimed
EP-4561379-B1 AEROSOL-GENERATING ARTICLE WITH AN ISOLATED AVERSIVE COMPONENT PHILIP MORRIS PRODUCTS SA (CH) 2026-03-25 — — EP claimed
EP-4561378-B1 AEROSOL-GENERATING ARTICLE WITH AVERSIVE AGENT PHILIP MORRIS PRODUCTS SA (CH) 2026-03-25 — — EP claimed
EP-4694699-A2 COMPOSITIONS AND METHODS OF CONTROLLING MAMMALIAN SATIETY VitaKey Inc. (US) 2026-02-18 — — EP claimed
US-20260041141-A1 AEROSOL-GENERATING ARTICLE WITH AN ISOLATED AVERSIVE COMPONENT PHILIP MORRIS PRODUCTS SA (CH) 2026-02-12 — — US claimed
US-20250339680-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2025-11-06 — — US claimed
US-20250331550-A1 AEROSOL-GENERATING ARTICLE EMBEDDED AVERSIVE AGENT PHILIP MORRIS PRODUCTS SA (CH) 2025-10-30 — — US claimed
US-20250331549-A1 AEROSOL-GENERATING ARTICLE WITH AVERSIVE AGENT PHILIP MORRIS PRODUCTS SA (CH) 2025-10-30 — — US claimed
WO-2008119527-A2 AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) 2008-10-09 — — WO claimed
WO-2008119526-A1 AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) 2008-10-09 — — WO claimed
CN-101273738-A Method for preparing recombined sour milk drinks having higher viable bacteria counts at normal temperature BEIJING FUMENGTE BIOTECHNOLOGY (CN) 2008-10-01 — — CN claimed
CN-101273736-A Method for preparing fermented milk having higher viable counts at normal temperature BEIJING FUMENGTE BIOTECHNOLOGY (CN) 2008-10-01 — — CN claimed
CN-100422737-C Preparation method of 'Xue Fu Zhu Yu' capsule and quality standard thereof TIANJIN HONGRENTANG PHARMACEUT (CN) 2008-10-01 — — CN claimed
EP-1972203-A1 Use of 4-hydroxychalkon derivatives for masking an unpleasant taste Symrise GmbH & Co. KG (DE) 2008-09-24 — — EP claimed
US-20080227867-A1 USE OF 4-HYDROXYCHALCONE DERIVATIVES FOR MASKING AN UPLEASANT TASTE SYMRISE GMBH & CO. KG (DE) 2008-09-18 — — US claimed
CN-1996008-A Identification method for Chinese globe flower and amygdalin in Chinese globe flower antipyretic capsule NINGXIA QIYUAN PHARMACEUTICAL (CN) 2007-07-11 — — CN claimed
CN-1730027-A Method for preparing anti-hepatitis active part from swertia main pharmaceutical plant QINGHAI PULANTE PHARMACEUTICAL (CN) 2006-02-08 — — CN claimed
CN-1634520-A Preparation process of Tibet capilary artemisia BEIJING PULANTE PHARMACEUTICAL (CN) 2005-07-06 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227867-A1 USE OF 4-HYDROXYCHALCONE DERIVATIVES FOR MASKING AN UPLEASANT TASTE TAS2R45, TAS2R43, TAS2R30 STAT3 4885/4885EPHX2 626/4885KDM4E 1299/4885
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields PTK2, GSK3B, MTOR STAT3 103/4885EPHX2 3779/4885KDM4E 2098/4885
US-20260041141-A1 AEROSOL-GENERATING ARTICLE WITH AN ISOLATED AVERSIVE COMPONENT ATXN10, ATXN2, TAS2R60 STAT3 2639/4885EPHX2 2102/4885KDM4E 4327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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