Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22662484 | 0.83 | STAT3 (0.61) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| SCHEMBL1031187 | 0.83 | STAT3 (0.61) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| SCHEMBL22662483 | 0.83 | STAT3 (0.61) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| SCHEMBL10307500 | 0.80 | STAT3 (0.39) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| SCHEMBL29655170 | 0.78 | STAT3 (0.61) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| Swertiamarin SCHEMBL4447545 | 0.78 | BACE1 (0.43) | STAT3KDM4EPOLBGAAMAPT | |
| SCHEMBL10307294 | 0.77 | STAT3 (0.49) | STAT3EPHX2HSP90AA1SLC28A3KDM4E | |
| Swertiamarin SCHEMBL422560 | 0.77 | STAT3 (0.57) | STAT3KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL29655393 | 0.71 | STAT3 (0.36) | STAT3SLC28A3 | |
| SCHEMBL29426019 | 0.71 | SLC28A3 (0.36) | STAT3SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | STAT3 2027/4885EPHX2 3756/4885HSP90AA1 600/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | STAT3 2027/4885EPHX2 3756/4885HSP90AA1 600/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | STAT3 2027/4885EPHX2 3756/4885HSP90AA1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.