Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 3/20 | 0.37 |
| ▸ | PLK4 | O00444 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312198 | 0.90 | IGF1R (0.42) | MAPTMAPK1PAK4PLK4LMNA | |
| SCHEMBL10312165 | 0.89 | NPSR1 (0.42) | KCNH3MAPTMAPK1PAK4PLK4 | |
| SCHEMBL10312195 | 0.89 | PAK4 (0.48) | KCNH3MAPTMAPK1PAK4PLK4 | |
| SCHEMBL10312133 | 0.89 | NTRK1 (0.39) | KCNH3CHEK1SLC2A1NTRK1JAK3 | |
| SCHEMBL10312211 | 0.84 | IGF1R (0.50) | PAK4PLK4NTRK1BTKJAK2 | |
| SCHEMBL10312203 | 0.81 | FLT3 (0.38) | PAK4PLK4CHEK1CDK1CDK4 | |
| SCHEMBL10312103 | 0.81 | HRH4 (0.47) | MAPTPAK4PLK4CHEK1CDK1 | |
| SCHEMBL10312153 | 0.80 | PKM (0.40) | MAPTPAK4PLK4LMNAPOLB | |
| SCHEMBL10312129 | 0.79 | KDM4E (0.41) | MAPK1LMNASLC2A1SMN1; SMN2IGF1R | |
| SCHEMBL10312189 | 0.79 | PAK4 (0.51) | PAK4PLK4FLT3NTRK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | STK25, STK35, SGK2 | KCNH3 2257/4885MAPT 1313/4885MAPK1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.