Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312363 | 0.85 | MAPK1 (0.50) | TDP1ESR2LMNAAPOBEC3GESR1 | |
| SCHEMBL10312389 | 0.84 | KMT2A (0.51) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL11184672 | 0.82 | CCR5 (0.56) | TDP1CCR5ESR2NR1H3PTGES | |
| SCHEMBL5190090 | 0.81 | TDP1 (0.71) | TDP1CCR5ESR2PTGESALDH1A1 | |
| SCHEMBL10312373 | 0.81 | ESR1 (0.57) | LMNAESR1HSD11B1NR1I2MAPK1 | |
| SCHEMBL7017780 | 0.79 | TDP1 (0.50) | TDP1CCR5NR1H3PTGESALDH1A1 | |
| SCHEMBL3621820 | 0.79 | TDP1 (0.50) | TDP1CCR5NR1H3PTGESALDH1A1 | |
| SCHEMBL9278436 | 0.79 | ESR2 (0.56) | TDP1CCR5ESR2NR1H3ALDH1A1 | |
| SCHEMBL15677252 | 0.78 | CNR2 (0.56) | ALDH1A1MAPT | |
| SCHEMBL8356647 | 0.78 | TDP1 (0.62) | TDP1CCR5PTGESESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828879-B2 | Silicon-containing composition having sulfonamide group for forming resist underlayer film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| US-7696177-B2 | Anti-hypercholesterolemic compounds | MERCK SHARP & DOHME CORP. (US) | 2010-04-13 | — | — | US | disclosed |
| US-20100004184-A1 | Anti-hypercholesterolemic compounds | MERCK SHARP & DOHME CORP. | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004184-A1 | Anti-hypercholesterolemic compounds | PCSK9, SLC10A1, NPC1 | TDP1 4666/4885CCR5 3322/4885ESR2 773/4885 |
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | STS, SI, MUS81 | TDP1 2589/4885CCR5 4824/4885ESR2 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.