Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 5/20 | 0.52 |
| ▸ | SAT1 | P21673 | 3/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589467 | 1.00 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL11106382 | 0.97 | TSHR (0.93) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL31758396 | 0.94 | TSHR (0.78) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL4166725 | 0.94 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL10045106 | 0.94 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL20922334 | 0.94 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL13895399 | 0.94 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL5847137 | 0.94 | TSHR (0.88) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL36957 | 0.94 | — | — | |
| SCHEMBL21132324 | 0.91 | TSHR (0.82) | TSHRCYP2C19MEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295180-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| CN-109906215-B | Continuous production of 2-methylene alkanals | OQ化学有限责任公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3600307-B1 | COMPOSITIONS FOR USE IN METHODS OF INHIBITING PROTEIN KINASES | UNIV HOUSTON SYSTEM (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-107068680-B | Integrated circuit device | 三星电子株式会社 | 2020-10-23 | — | — | CN | disclosed |
| EP-3268008-B1 | COMPOUNDS THAT ARE ANALOGS OF SQUALAMINE, USED AS ANTIBACTERIAL AGENTS | VIRBAC (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3351540-A1 | CYCLOHEXANE DERIVATIVE OR STEREOISOMER OR SALT THEREOF, AND PREPARATION AND USE THEREOF | Zhejiang Jingxin Pharmaceutical Co., Ltd. (CN) | 2018-07-25 | — | — | EP | disclosed |
| WO-2018015196-A1 | SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | WO | disclosed |
| EP-2499277-B1 | METAL INK COMPOSITIONS, CONDUCTIVE PATTERNS, METHODS, AND DEVICES | UNIV CARNEGIE MELLON (US) | 2017-09-27 | — | — | EP | disclosed |
| US-8481243-B2 | Resin and photoresist composition comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20120178021-A1 | RESIN AND PHOTORESIST COMPOSITION COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295180-A1 | PROTEIN DEGRADERS AND USES THEREOF | MDM2, CUL1, PSMG3 | TSHR 3432/4885CYP2C19 3642/4885MEN1 2643/4885 |
| US-20120178021-A1 | RESIN AND PHOTORESIST COMPOSITION COMPRISING THE SAME | SULT1A1, SULT1E1, C1S | TSHR 3515/4885CYP2C19 707/4885MEN1 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.