SCHEMBL10315678

SCHEMBL10315678

c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccc6c(c7ccccc7n6-c6ccc(N(c7ccccc7)c7ccccc7)cc6)c54)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ TSPO P30536 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ KMT2A Q03164 2/20 0.31
▸ IL1R1 P14778 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ JAK2 O60674 1/20 0.30
▸ JAK3 P52333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17248279 0.94 L3MBTL1 (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL24252004 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL18505027 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL31869 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL17426370 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL19769605 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL19769643 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL24230588 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL22003581 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL18124896 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF AHR, ARNT, NAT1 L3MBTL1 2732/4885KDM4E 2441/4885ATM 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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