SCHEMBL103163

SCHEMBL103163

O=[C]c1c(Cl)c(Cl)c(Cl)c(Cl)c1[C]=O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312139 0.92 MEN1 (0.42) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL102019 0.89 MEN1 (0.47) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL101012 0.88 MEN1 (0.37) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL5432916 0.85 MEN1 (0.33) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL10490624 0.76 MEN1 (0.32) MEN1ALDH1A1TP53CYP3A4MAPT
SCHEMBL777074 0.70
SCHEMBL1312705 0.70 CYP3A4 (0.50) MEN1ALDH1A1CYP3A4MAPTHPGD
SCHEMBL10611655 0.68 NOTUM (0.31)
SCHEMBL1312947 0.67 CYP3A4 (0.47) MEN1ALDH1A1CYP3A4MAPTHPGD
SCHEMBL102072 0.67 CYP3A4 (0.39) ALDH1A1CYP3A4HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084988-A Polymerization monomer for preparing beta-1, 3 glucan and polymerization method 山东大学 2024-05-28 CN claimed
WO-2024081372-A1 PROCESSES FOR THE PREPARATION OF THE AGENT-LINKER CONJUGATE CL2A-SN-38 AND THE IMMUNOCONJUGATES SACITUZUMAB GOVITECAN AND LABETUZUMAB GOVETICAN GILEAD SCIENCES, INC. (US) 2024-04-18 WO claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 EP claimed
EP-3720854-B1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING SPA (IT) 2021-04-21 EP claimed
US-10822371-B2 Solid phase synthesis of NIR fluorescent probe BRACCO IMAGING S.P.A. (IT) 2020-11-03 US claimed
EP-3720854-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE Bracco Imaging SpA (IT) 2020-10-14 EP claimed
US-20200317722-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING S.P.A. (IT) 2020-10-08 US claimed
CN-111356691-A Solid phase synthesis of NIR fluorescent probes 伯拉考成像股份公司 2020-06-30 CN claimed
WO-2019110639-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE BRACCO IMAGING SPA (IT) 2019-06-13 WO claimed
EP-3400217-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2018-11-14 EP claimed
WO-2006012425-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2006-02-02 WO claimed
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION, A CORPORATION OF THE STATE OF DELAWARE (US) 2005-05-19 US claimed
EP-1521762-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2005-04-13 EP claimed
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor CORIXA CORPORATION 2004-12-30 US claimed
WO-2004005308-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2004-01-15 WO claimed
US-6355615-B1 CYCLIC POLYAMIDEESTER COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 2002-03-12 US claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 WO claimed
US-4175185-A ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION MEIJI SEIKA KAISHA LTD. (JP) 1979-11-20 US claimed
US-3996043-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1976-12-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317722-A1 SOLID PHASE SYNTHESIS OF NIR FLUORESCENT PROBE MKI67, SSTR5, AURKA MEN1 1675/4885ALDH1A1 3804/4885TP53 11/4885
US-20040267007-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors and intermediates therefor DDOST, STT3A, STT3B MEN1 3860/4885ALDH1A1 1755/4885TP53 3230/4885
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor DDOST, AGL, GALE MEN1 3756/4885ALDH1A1 1633/4885TP53 2990/4885
US-10822371-B2 Solid phase synthesis of NIR fluorescent probe MKI67, SSTR5, AURKA MEN1 1675/4885ALDH1A1 3804/4885TP53 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.