Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312947 | 0.83 | CYP3A4 (0.47) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL103899 | 0.80 | — | — | |
| SCHEMBL102072 | 0.80 | CYP3A4 (0.39) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL3695890 | 0.74 | HPGD (0.50) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL101012 | 0.73 | MEN1 (0.37) | CYP3A4HPGDMAPK1ALDH1A1MEN1 | |
| SCHEMBL94929 | 0.72 | ALDH1A1 (0.45) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL10701289 | 0.70 | MAPK1 (0.33) | CYP3A4MAPK1AHRTDP1 | |
| SCHEMBL1312475 | 0.70 | MAPK1 (0.36) | CYP3A4TSHRMAPK1AHRTDP1 | |
| SCHEMBL101710 | 0.70 | CYP3A4 (0.33) | CYP3A4ALDH1A1 | |
| SCHEMBL103163 | 0.70 | MEN1 (0.42) | CYP3A4HPGDMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234087-B2 | Preparation for initiating radical reactions | UNITED INITIATORS GMBH & CO. KG (DE) | 2016-01-12 | — | — | US | claimed |
| EP-2288652-B1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO KG (DE) | 2012-09-19 | — | — | EP | claimed |
| EP-2130858-B1 | Preparations to initiate radical reactions | UNITED INITIATORS GMBH & CO KG (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20110272628-A1 | Preparation For Initiating Radical Reactions | UNITED INITIATORS GMBH (DE) | 2011-11-10 | — | — | US | claimed |
| EP-2288652-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | United Initiators GmbH & Co. KG (DE) | 2011-03-02 | — | — | EP | claimed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | claimed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | claimed |
| US-9234087-B2 | Preparation for initiating radical reactions | UNITED INITIATORS GMBH & CO. KG (DE) | 2016-01-12 | — | — | US | disclosed |
| EP-2288652-B1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO KG (DE) | 2012-09-19 | — | — | EP | disclosed |
| EP-2130858-B1 | Preparations to initiate radical reactions | UNITED INITIATORS GMBH & CO KG (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-20110272628-A1 | Preparation For Initiating Radical Reactions | UNITED INITIATORS GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
| EP-2288652-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | United Initiators GmbH & Co. KG (DE) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | disclosed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | disclosed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | disclosed |