Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954022 | 1.00 | CHRM3 (0.60) | CHRM3CHRM2CHRM1KCNA3 | |
| SCHEMBL12953202 | 0.84 | CHRM3 (0.45) | CHRM3CHRM2CHRM1 | |
| SCHEMBL13187336 | 0.84 | CHRM3 (0.42) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12954023 | 0.81 | CHRM3 (0.44) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12954109 | 0.81 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12953201 | 0.80 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12954020 | 0.78 | CHRM3 (0.62) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12953184 | 0.76 | CHRM3 (0.47) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5442969 | 0.76 | CHRM3 (0.89) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5442971 | 0.76 | CHRM3 (0.89) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682142-B1 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2012-07-11 | — | — | EP | disclosed |
| WO-2009036243-A1 | NOVEL COMBINATION OF THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |