Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187336 | 0.87 | CHRM3 (0.42) | CHRM3CHRM2CHRM1DRD2SLC22A1 | |
| SCHEMBL12954109 | 0.84 | CHRM3 (0.60) | CHRM3CHRM2CHRM1DRD2CHRM4 | |
| SCHEMBL12954022 | 0.84 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12954023 | 0.84 | CHRM3 (0.44) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL10316394 | 0.84 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12953201 | 0.83 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CYP3A4ATM | |
| SCHEMBL12954020 | 0.81 | CHRM3 (0.62) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL12953184 | 0.79 | CHRM3 (0.47) | CHRM3CHRM2CHRM1CYP3A4CYP2D6 | |
| SCHEMBL12953549 | 0.77 | CHRM3 (0.65) | CHRM3CHRM2CHRM1CYP3A4CYP2D6 | |
| SCHEMBL12953389 | 0.76 | CHRM2 (0.66) | CHRM3CHRM2CHRM1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677795-B1 | MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2011-01-05 | — | — | EP | disclosed |