Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953201 | 0.89 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CYP3A4ATM | |
| SCHEMBL12954020 | 0.87 | CHRM3 (0.62) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL12953549 | 0.81 | CHRM3 (0.65) | CHRM3CHRM2CHRM1CYP3A4CYP2D6 | |
| SCHEMBL12954109 | 0.81 | CHRM3 (0.60) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL12953202 | 0.79 | CHRM3 (0.45) | CHRM3CHRM2CHRM1CYP3A4CYP2D6 | |
| SCHEMBL13187336 | 0.79 | CHRM3 (0.42) | CHRM3CHRM2CHRM1CYP3A4CYP2D6 | |
| SCHEMBL12953791 | 0.79 | CHRM3 (0.67) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL12954023 | 0.78 | CHRM3 (0.44) | CHRM3CHRM2CHRM1ATML3MBTL1 | |
| SCHEMBL13717103 | 0.78 | CHRM3 (0.76) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12954024 | 0.78 | CHRM2 (0.69) | CHRM3CHRM2CHRM1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677795-B1 | MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2011-01-05 | — | — | EP | disclosed |