SCHEMBL10316630

CC1(C)CC(c2c(C(=O)O)c(C3CC(C)(C)NC(C)(C)C3)c(C(=O)OC(=O)c3c(C(=O)O)c(C4CC(C)(C)NC(C)(C)C4)c(C(=O)O)c(C4CC(C)(C)NC(C)(C)C4)c3C3CC(C)(C)NC(C)(C)C3)c(C3CC(C)(C)NC(C)(C)C3)c2C(=O)O)CC(C)(C)N1

nearest known ligand 0.38

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GAA	P10253	2/20	0.38

▸	ALOX15	P16050	1/20	0.34

▸	MEN1	O00255	1/20	0.31

▸	MAPK1	P28482	1/20	0.31

▸	KMT2A	Q03164	1/20	0.31

▸	TSHR	P16473	2/20	0.31

▸	EZH2	Q15910	2/20	0.31

▸	POLB	P06746	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL313687	0.89	ALOX15 (0.39)	GAAALOX15KMT2ATSHREZH2
SCHEMBL10316625	0.89	ALOX15 (0.39)	GAAALOX15KMT2ATSHREZH2
SCHEMBL451727	0.86	ALOX15 (0.41)	GAAALOX15KMT2ATSHREZH2
SCHEMBL6139806	0.82	POLB (0.39)	GAAALOX15KMT2ATSHREZH2
SCHEMBL30960383	0.78	GAA (0.41)	GAAMEN1KMT2ATSHREZH2
SCHEMBL17491073	0.71	GAA (0.38)	GAAALOX15MEN1KMT2AEZH2
SCHEMBL2233519	0.70	ALOX15 (0.44)	GAAALOX15KMT2ATSHREZH2
SCHEMBL453481	0.68	ALOX15 (0.48)	GAAALOX15KMT2ATSHREZH2
SCHEMBL11176536	0.68	TSHR (0.33)	TSHR
SCHEMBL17491074	0.68	ALOX15 (0.38)	GAAALOX15KMT2ATSHREZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2476717-A1	POLYAMIDE AND POLYAMIDE COMPOSITION	Asahi Kasei Chemicals Corporation (JP)	2012-07-18	—	—	EP	disclosed