SCHEMBL451727

SCHEMBL451727

CC1(C)CC(c2c(C(=O)O)c(C3CC(C)(C)NC(C)(C)C3)c(C(=O)O)c(C3CC(C)(C)NC(C)(C)C3)c2C(=O)O)CC(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
GAA P10253 2/20 0.40
POLB P06746 2/20 0.37
EZH2 Q15910 3/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.34
TP53 P04637 1/20 0.33
KDM1A O60341 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10316625 0.96 ALOX15 (0.39) ALOX15GAAPOLBEZH2HTT
SCHEMBL313687 0.96 ALOX15 (0.39) ALOX15GAAPOLBEZH2HTT
SCHEMBL6139806 0.89 POLB (0.39) ALOX15GAAPOLBEZH2HTT
SCHEMBL10316630 0.86 GAA (0.38) ALOX15GAAPOLBEZH2KMT2A
SCHEMBL2233519 0.81 ALOX15 (0.44) ALOX15GAAPOLBEZH2HTT
SCHEMBL30960383 0.79 GAA (0.41) GAAPOLBEZH2KMT2ATSHR
SCHEMBL453481 0.79 ALOX15 (0.48) ALOX15GAAPOLBEZH2HTT
SCHEMBL10924489 0.79 TP53 (0.33) ALOX15GAAPOLBEZH2HTT
SCHEMBL17491073 0.79 GAA (0.38) ALOX15GAAPOLBEZH2HTT
SCHEMBL4012295 0.78 ALOX15 (0.41) ALOX15GAAPOLBEZH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745497-A Semi-aromatic polyamide resin and preparation method and application thereof 南京开创新材料科技有限公司 2021-05-04 CN claimed
CN-112679728-A Semi-aromatic polyamide resin and preparation method thereof 南京开创新材料科技有限公司 2021-04-20 CN claimed
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP claimed
EP-0151042-B1 POLYACETAL RESIN COMPOSITION AND MOULDED PRODUCTS THEREOF POLYPLASTICS CO. LTD. (JP) 1988-08-17 EP claimed
US-4730015-A BENZOTRIAZOLE AND PIPERIDINE STABILIZER POLYPLASTICS CO., LTD. (JP) 1988-03-08 US claimed
US-6384179-B1 None US disclosed
EP-4686333-A1 PELLET MIXTURE, RADIO WAVE ABSORBER, RADIO WAVE ABSORBING ARTICLE, AND METHOD FOR MANUFACTURING RADIO WAVE ABSORBER FUJIFILM Corporation (JP) 2026-01-28 EP disclosed
US-12534299-B2 Antimicrobial/antiviral conveyor belt ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2026-01-27 US disclosed
US-20260018323-A1 PELLET MIXTURE, RADIO WAVE ABSORBER, RADIO WAVE ABSORBING ARTICLE, AND METHOD FOR PRODUCING RADIO WAVE ABSORBER FUJIFILM CORPORATION (JP) 2026-01-15 US disclosed
EP-4635923-A1 RESIN COMPOSITION FOR LAMINATED GLASS INTERLAYER FILM, LAMINATED GLASS INTERLAYER FILM, AND LAMINATED GLASS Dow-Mitsui Polychemicals Co., Ltd. (JP) 2025-10-22 EP disclosed
US-12441065-B2 Formed article, welding method, and method of manufacturing formed article ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-10-14 US disclosed
EP-4577599-A1 FLAME-RETARDANT POLYAMIDE COMPOSITION BASF SE (DE) 2025-07-02 EP disclosed
EP-0171941-B1 WEATHER RESISTANT POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 1990-03-21 EP disclosed
US-4861814-A ANTIOXIDANT, METAL CARBOXYLATE OF TERTIARY NITROGEN-CONTAINING BASIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1989-08-29 US disclosed
EP-0300573-A1 Molded article comprising a weather-resistant polyoxymethylene composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-01-25 EP disclosed
EP-0151042-B1 POLYACETAL RESIN COMPOSITION AND MOULDED PRODUCTS THEREOF POLYPLASTICS CO. LTD. (JP) 1988-08-17 EP disclosed
US-4730015-A BENZOTRIAZOLE AND PIPERIDINE STABILIZER POLYPLASTICS CO., LTD. (JP) 1988-03-08 US disclosed
EP-0151042-A2 Polyacetal resin composition and moulded products thereof POLYPLASTICS CO. LTD. (JP) 1985-08-07 EP disclosed
US-4487870-A BLEND OF ETHYLENE-VINYL ACETATE COPOLYMER WITH PHOTOSTABILIZER EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed
US-4038218-A SPRAY DRYING KAO SOAP CO., LTD. (JA) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534299-B2 Antimicrobial/antiviral conveyor belt POLR1C, SLC30A6, ATP6V0C ALOX15 2627/4885GAA 2499/4885POLB 66/4885
US-20260018323-A1 PELLET MIXTURE, RADIO WAVE ABSORBER, RADIO WAVE ABSORBING ARTICLE, AND METHOD FOR PRODUCING RADIO WAVE ABSORBER RAD1, POT1, MCM4 ALOX15 4120/4885GAA 4876/4885POLB 3015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.