Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19704405 | 0.87 | MGLL (0.40) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL20930969 | 0.87 | MGLL (0.40) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL21158066 | 0.87 | MGLL (0.40) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL20616617 | 0.86 | MGLL (0.38) | MGLLFAAHALDH1A1 | |
| SCHEMBL21577922 | 0.84 | MGLL (0.38) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL21158545 | 0.81 | MGLL (0.38) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL21577840 | 0.79 | FAAH (0.36) | MGLLFAAHALDH1A1 | |
| SCHEMBL28651505 | 0.76 | TSHR (0.40) | TSHRMGLLFAAHALDH1A1GMNN | |
| SCHEMBL24916383 | 0.74 | MGLL (0.40) | MGLLFAAHALDH1A1CYP1A2 | |
| SCHEMBL16136724 | 0.73 | FAAH (0.46) | TSHRMGLLFAAHALDH1A1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476741-A1 | Pyrrolidine-2,5-Dione derivatives for use in friction modification | Afton Chemical Corporation (US) | 2012-07-18 | — | — | EP | disclosed |