SCHEMBL10316741

SCHEMBL10316741

CC(C)(OCCOP(=O)(O)O)C(C)(C)OP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.39
LPAR2 Q9HBW0 6/20 0.39
LPAR1 Q92633 4/20 0.39
SMPD1 P17405 3/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513481 0.79 LPAR3 (0.45) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL5963785 0.78 LMNA (0.40) SMPD1PGK1PGK2
SCHEMBL10316879 0.74 LPAR3 (0.42) LPAR3LPAR2LPAR1SMPD1PGK1
SCHEMBL811703 0.72 LPAR3 (0.55) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL27985564 0.72 LPAR3 (0.39) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL28683623 0.70 LPAR3 (0.40) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL6514945 0.69 LPAR3 (0.52) LPAR3LPAR2LPAR1PGK1PGK2
SCHEMBL10317032 0.68 LPAR3 (0.49) LPAR3LPAR2LPAR1SMPD1
SCHEMBL5963603 0.68 SMPD1 (0.38) LPAR3LPAR2LPAR1SMPD1
SCHEMBL1514200 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2476684-B1 Method for manufacturing alkyl-phosphates LANXESS DEUTSCHLAND GMBH (DE) 2017-07-19 EP claimed
EP-2476685-B1 Method for manufacturing alkyl-phosphates LANXESS DEUTSCHLAND GMBH (DE) 2017-08-02 EP disclosed
EP-2476686-B1 Method for manufacturing alkyl-phosphates LANXESS DEUTSCHLAND GMBH (DE) 2017-08-02 EP disclosed
EP-2476684-B1 Method for manufacturing alkyl-phosphates LANXESS DEUTSCHLAND GMBH (DE) 2017-07-19 EP disclosed
US-8846967-B2 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2014-09-30 US disclosed
EP-2479179-A1 Process for the preparation of alkylphosphates LANXESS Deutschland GmbH (DE) 2012-07-25 EP disclosed
EP-2479178-A1 Process for the preparation of alkylphosphates LANXESS Deutschland GmbH (DE) 2012-07-25 EP disclosed
EP-2479180-A1 Process for the preparation of alkylphosphates LANXESS Deutschland GmbH (DE) 2012-07-25 EP disclosed
US-20120184764-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
US-20120184766-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
US-20120184765-A1 Process for preparing alkyl phosphates LANXESS DEUTSCHLAND GMBH (DE) 2012-07-19 US disclosed
EP-2476685-A1 Method for manufacturing alkyl-phosphates Lanxess Deutschland GmbH (DE) 2012-07-18 EP disclosed
EP-2476686-A1 Method for manufacturing alkyl-phosphates Lanxess Deutschland GmbH (DE) 2012-07-18 EP disclosed
EP-2476684-A1 Method for manufacturing alkyl-phosphates Lanxess Deutschland GmbH (DE) 2012-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184764-A1 Process for preparing alkyl phosphates PNKP, PHOSPHO1, DCTPP1 LPAR3 361/4885LPAR2 430/4885LPAR1 409/4885
US-20120184766-A1 Process for preparing alkyl phosphates PHOSPHO1, PNKP, PLCB3 LPAR3 354/4885LPAR2 380/4885LPAR1 418/4885
US-20120184765-A1 Process for preparing alkyl phosphates PNKP, PHOSPHO1, DCTPP1 LPAR3 361/4885LPAR2 430/4885LPAR1 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.