Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | CTSA | P10619 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672424 | 0.89 | FFAR1 (0.58) | FFAR1CTSAPTGDR2FFAR4 | |
| SCHEMBL12986211 | 0.87 | PTGDR2 (0.51) | FFAR1PTPN1PTGDR2FFAR4 | |
| SCHEMBL19212490 | 0.85 | PTGDR2 (0.44) | FFAR1CTSAPTPN1SIRT2PTGDR2 | |
| SCHEMBL1672699 | 0.81 | HTR7 (0.48) | FFAR1CTSAHTR7PTGDR2KMT2A | |
| SCHEMBL1107166 | 0.79 | SIRT2 (0.52) | SIRT2MEN1KMT2AFFAR4 | |
| SCHEMBL6721718 | 0.79 | HTR7 (0.52) | FFAR1CTSAHTR7PTGDR2KMT2A | |
| SCHEMBL21475912 | 0.79 | HTR7 (0.58) | FFAR1PTPN1HTR7SIRT2FFAR4 | |
| SCHEMBL5039715 | 0.79 | PTPN1 (0.55) | FFAR1PTPN1HTR7SIRT2CNR2 | |
| SCHEMBL8200129 | 0.78 | JAK2 (0.49) | FFAR1PTPN1HTR7PDE4DKMT2A | |
| SCHEMBL3614087 | 0.77 | HTR7 (0.51) | CTSAHTR7PTGDR2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701932-B1 | TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME | CIPLA LTD (IN) | 2012-07-18 | — | — | EP | disclosed |