Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | SELP | P16109 | 2/20 | 0.48 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587585 | 0.88 | SELP (0.47) | SELPSELPLGPDE4DFFAR1HTR7 | |
| SCHEMBL8192753 | 0.88 | PDE4D (0.55) | JAK2JAK3PDE4DFFAR1HTR7 | |
| SCHEMBL8201063 | 0.86 | ALDH1A1 (0.51) | SELPSELPLGPDE4DSLC7A5HPGD | |
| SCHEMBL8710187 | 0.85 | PPARA (0.52) | SELPSELPLG | |
| SCHEMBL6553321 | 0.85 | ALDH1A1 (0.50) | SELPSELPLGPDE4DSLC7A5HPGD | |
| SCHEMBL8205873 | 0.84 | PPARA (0.44) | SELPSELPLGPDE4DFFAR1HTR7 | |
| SCHEMBL7031826 | 0.83 | HTR7 (0.63) | JAK2JAK3SELPFFAR1HTR7 | |
| SCHEMBL17124777 | 0.81 | JAK2 (0.55) | JAK2JAK3HTR7HPGDCYP1A2 | |
| SCHEMBL8709712 | 0.81 | ALDH1A1 (0.48) | SLC7A5HPGDGABRA1GABRB2 | |
| SCHEMBL7735763 | 0.80 | PTPN1 (0.54) | JAK2JAK3FFAR1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840606-B1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORP (US) | 2000-06-07 | — | — | EP | disclosed |